RNF103-CHMP3

Across TCGA patient cohorts, RNF103-CHMP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,599 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNF103-CHMP3-associated proteins across cancer lineages are SPCS2, SSR3_S105, and SYTL3_S185. Each is linked with RNF103-CHMP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF103-CHMP3-to-partner and partner-to-RNF103-CHMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF103-CHMP3 versus SPCS2 in LSCC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF103-CHMP3→partner) and Y-score (partner→RNF103-CHMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPCS2 →	-0.430	-0.234	<.001	<.001	3	3
LSCC	SSR3_S105 →	-0.765	-0.363	.002	<.001	3	3
GBM	SYTL3_S185 →	-0.631	-0.342	.006	.003	3	3
LSCC	THEMIS2 →	-0.378	-0.304	<.001	<.001	3	3
LSCC	TRIM22 →	-0.348	-0.270	.002	.002	3	3
GBM	MYO1G →	-0.509	-0.241	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,599 associations by consensus.

RNF103-CHMP3 vs SPCS2 — LSCC

Explore this scatter interactively →