RNF10

Across TCGA patient cohorts, RNF10 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,429 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNF10-associated proteins across cancer lineages are PIK3R4_S853, SRSF9, and PRPF31. Each is linked with RNF10 in more than 4 cancer types. Because this analysis shows association rather than direction, both RNF10-to-partner and partner-to-RNF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNF10 versus PIK3R4_S853 in UCEC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF10→partner) and Y-score (partner→RNF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIK3R4_S853 →	-0.583	-0.339	.001	.002	3	5
LSCC	SRSF9 →	+0.450	+0.496	<.001	<.001	3	5
PDAC	PRPF31 →	+0.209	+0.221	.002	.009	3	4
LSCC	SCYL2 →	+0.272	+0.386	<.001	.001	3	4
UCEC	TMEM258 →	-0.862	-0.594	<.001	<.001	3	4
LSCC	SRSF9_S193 →	+0.737	+0.498	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,429 associations by consensus.

RNF10 vs PIK3R4_S853 — UCEC

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