RNF10

Across TCGA patient cohorts, RNF10 mutation is significantly associated with the RNA expression of many other genes, with 1,774 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF10-associated genes across cancer lineages are MTCO1P45, TRAJ46, and RNU6-575P. Each is linked with RNF10 in more than 2 cancer types. Because this analysis shows association rather than direction, both RNF10-to-partner and partner-to-RNF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCO1P45 grouped by RNF10-low versus RNF10-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF10→partner) and Y-score (partner→RNF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTCO1P45 →	+0.216	+4.659	<.001	.004	3	3
UCEC	TRAJ46 →	+0.163	+2.595	.002	.004	3	3
BRCA	RNU6-575P →	+0.543	+4.739	<.001	.005	3	2
HNSC	HMGN1P16 →	+0.230	+4.025	.005	.003	3	2
CESC	ZNF619P1 →	+0.036	+4.969	<.001	<.001	3	2
BLCA	MIR548AT →	+0.547	+3.173	.006	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,774 associations by consensus.

MTCO1P45 by RNF10 expression — LUAD

Explore this box plot interactively →