RNF10

Across TCGA cell cohorts, RNF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,474 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF10-associated GO terms across cancer lineages are Negative regulation of hippo signaling, Endosomal transport, and Process utilizing autophagic mechanism. Each is linked with RNF10 in more than 10 cancer types. Because this analysis shows association rather than direction, both RNF10-to-partner and partner-to-RNF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hippo signaling grouped by RNF10-low versus RNF10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF10→partner) and Y-score (partner→RNF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of hippo signaling →	+0.077	+0.502	<.001	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.068	+0.710	<.001	<.001	3	11
STOMACH	Process utilizing autophagic mechanism →	+0.059	+0.615	.003	.009	3	10
STOMACH	Autophagy →	+0.059	+0.615	.003	.009	3	10
OVARY	Vacuole organization →	+0.043	+0.442	.004	.009	3	10
STOMACH	Negative regulation of macroautophagy →	+0.078	+0.669	.002	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,474 associations by consensus.

Negative regulation of hippo signaling by RNF10 expression — STOMACH

Explore this box plot interactively →