RNASET2

Across TCGA patient cohorts, RNASET2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,627 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RNASET2-associated genes across cancer lineages are RPS6KA2-AS1, NCAPG, and SPC25. Each is linked with RNASET2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RNASET2-to-partner and partner-to-RNASET2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASET2 versus RPS6KA2-AS1 in CCRCC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASET2→partner) and Y-score (partner→RNASET2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RPS6KA2-AS1 →	+0.822	+0.597	<.001	<.001	3	6
GBM	NCAPG →	-1.203	-0.480	<.001	<.001	3	5
GBM	SPC25 →	-0.980	-0.435	<.001	.001	3	5
BRCA	SKA2 →	-0.703	-0.404	<.001	<.001	3	5
GBM	CDKN3 →	-0.929	-0.452	<.001	<.001	3	4
UCEC	BRIP1 →	-0.742	-0.489	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,627 associations by consensus.

RNASET2 vs RPS6KA2-AS1 — CCRCC

Explore this scatter interactively →