RNASE8

Across TCGA patient cohorts, RNASE8 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RNASE8-associated genes across cancer lineages are Fibroblasts. Each is linked with RNASE8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNASE8-to-partner and partner-to-RNASE8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by RNASE8-low versus RNASE8-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASE8→partner) and Y-score (partner→RNASE8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Fibroblasts →	+0.041	+5.797	<.001	.035	3	2

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Fibroblasts by RNASE8 expression — SKCM

Explore this box plot interactively →