RNA5SP474

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNA5SP474 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RNA5SP474 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNA5SP474 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNA5SP474 expression acts as an unfavorable survival marker, although some lineages such as UVM and BLCA show a favorable association.

UVM, KIRC, and BLCA are the cancer types where RNA5SP474 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSMedianAll0.7890.337.00355view →
KIRCDFSMedianII,III,IV0.5360.768.00240view →
BLCAOSTertileAll0.7610.655.00633view →
UCECDFSTertileIII,IV0.7220.830.03816view →
SKCMOSMedianAll0.8110.752.02513view →
STADOSTertileIII,IV0.5040.755.00512view →
UCSDFSMedianAll0.5540.309.01112view →
READDFSQuartileII,III,IV1.0000.584.00510view →
DLBCDFSQuartileIII,IV0.0700.833.0149view →
GBMOSMedianAll0.3460.478.0258view →
LIHCOSMedianIII,IV0.6830.416.0258view →
TGCTDFSQuartileII,III,IV0.7290.996.0456view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration