Across TCGA pan-cancer cohorts, RNA5SP474 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNA5SP474’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where RNA5SP474 RNA is repressed in tumor relative to normal tissue. In most cancer types RNA5SP474 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA, COAD, and CHOL are the cancer types where RNA5SP474 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP474 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.