RNA5SP385

Across TCGA pan-cancer cohorts, RNA5SP385 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNA5SP385 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNA5SP385 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNA5SP385 expression acts as an unfavorable survival marker, although some lineages such as STAD and BRCA show a favorable association.

MESO, UVM, and OV are the cancer types where RNA5SP385 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.252	0.581	<.001	162	view →
UVM	OS	Tertile	II,III,IV	0.211	0.727	<.001	126	view →
OV	OS	Tertile	II,III,IV	0.571	0.697	.009	48	view →
THCA	DFS	Tertile	II,III,IV	0.131	0.691	.001	36	view →
HNSC	DFS	Median	III,IV	0.180	0.432	.008	33	view →
READ	OS	Tertile	All	0.194	0.702	.001	27	view →
ACC	DFS	Tertile	All	0.121	0.673	.004	27	view →
STAD	DFS	Tertile	IV	1.000	0.311	.038	18	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
PCPG	DFS	Tertile	All	0.167	0.790	.017	12	view →
SKCM	OS	Tertile	IV	0.133	0.621	.026	9	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNA5SP385–MESO (OS)

Open the MESO breakdown →