RNA5SP385

Across TCGA pan-cancer cohorts, RNA5SP385 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNA5SP385’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNA5SP385 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNA5SP385 is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

LUSC, ESCA, and LUAD are the cancer types where RNA5SP385 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNA5SP385 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.222	.007	3	view →
ESCA	All	II,III,IV	−0.525	<.001	2	view →
LUAD	All	All	+0.240	.013	2	view →
KIRC	Male	All	+0.048	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNA5SP385–LUSC

Open the LUSC breakdown →