Q-omics provides the consensus-scored RNA5SP385 profile across patient tissues and cancer cell-line models. RNA5SP385 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, RNA5SP385 is differentially expressed in 4, with the highest sampling consensus in LUSC. Additionally, RNA5SP385 RNA expression shows 8,983 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight MESO, LUSC, and ESCA as cancer lineages where RNA5SP385 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNA5SP385 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNA5SP385 survival associations across molecular data types. RNA5SP385 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNA5SP385 RNA expression–survival associations across cancer types. High RNA5SP385 expression shows unfavorable associations in MESO, UVM, OV, THCA, HNSC and ACC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for RNA5SP385 RNA expression.
This table summarizes RNA5SP385 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for RNA5SP385. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNA5SP385 shows lower tumor expression in ESCA and higher tumor expression in LUSC, LUAD and KIRC. The LUSC box plot shows higher RNA5SP385 RNA expression in tumor versus normal tissue (log2 FC = +0.222, t-test p = .007).
This table shows molecular features associated with RNA5SP385 in patient tissues and cancer cell lines. In patient samples, RNA5SP385 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
