RMND5B

Across TCGA patient cohorts, RMND5B mutation is significantly associated with the RNA expression of many other genes, with 1,762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMND5B-associated genes across cancer lineages are RNU6-492P, RNA5SP524, and RNA5SP113. Each is linked with RMND5B in more than 1 cancer types. Because this analysis shows association rather than direction, both RMND5B-to-partner and partner-to-RMND5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-492P grouped by RMND5B-low versus RMND5B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMND5B→partner) and Y-score (partner→RMND5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-492P →	+0.353	+7.954	<.001	.008	3	2
LUAD	RNA5SP524 →	+0.328	+7.930	<.001	.008	3	2
UCEC	RNA5SP113 →	+0.368	+2.702	<.001	.003	3	2
UCEC	COTL1P2 →	+0.176	+1.503	.004	.009	3	2
LUSC	LINGO1-AS2 →	+0.214	+5.404	<.001	.005	3	2
HNSC	RNA5SP409 →	+0.238	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,762 associations by consensus.

RNU6-492P by RMND5B expression — HNSC

Explore this box plot interactively →