RMDN2

Across TCGA patient cohorts, RMDN2 mutation is significantly associated with the RNA expression of many other genes, with 2,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RMDN2-associated genes across cancer lineages are COQ2, DHDDS, and UBR7. Each is linked with RMDN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RMDN2-to-partner and partner-to-RMDN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COQ2 grouped by RMDN2-low versus RMDN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RMDN2→partner) and Y-score (partner→RMDN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	COQ2 →	+0.358	+2.559	.004	.008	3	3
UCEC	DHDDS →	+0.364	+1.726	<.001	.002	3	3
UCEC	UBR7 →	+0.480	+2.606	<.001	<.001	3	3
CESC	RN7SL248P →	+0.212	+7.584	<.001	<.001	3	3
UCEC	MSANTD3 →	+0.471	+2.332	<.001	<.001	3	3
SKCM	RASSF1 →	+0.415	+2.279	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,892 associations by consensus.

COQ2 by RMDN2 expression — SKCM

Explore this box plot interactively →