RIPOR2

Across TCGA patient cohorts, RIPOR2 mutation is significantly associated with the RNA expression of many other genes, with 3,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIPOR2-associated genes across cancer lineages are TAF13, MARCHF5, and GAN. Each is linked with RIPOR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RIPOR2-to-partner and partner-to-RIPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF13 grouped by RIPOR2-low versus RIPOR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR2→partner) and Y-score (partner→RIPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF13 →	+0.490	+1.949	<.001	<.001	3	4
UCEC	MARCHF5 →	+0.351	+1.191	.003	.004	3	3
UCEC	GAN →	+0.275	+1.726	.001	.001	3	3
BLCA	TSPY22P →	+0.331	+5.722	<.001	.001	3	3
UCEC	BAG3 →	+0.427	+1.624	<.001	<.001	3	3
UCEC	SUPV3L1 →	+0.264	+1.799	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

TAF13 by RIPOR2 expression — UCEC

Explore this box plot interactively →