RIMS1

Across TCGA cell cohorts, RIMS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,101 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RIMS1-associated GO terms across cancer lineages are Stress granule assembly, Positive regulation of post-translational protein modification, and Positive regulation of protein modification by small protein conjugation or removal. Each is linked with RIMS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RIMS1-to-partner and partner-to-RIMS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stress granule assembly grouped by RIMS1-low versus RIMS1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS1→partner) and Y-score (partner→RIMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Stress granule assembly →	+0.092	+0.980	<.001	.006	3	6
CNS	Positive regulation of post-translational protein modification →	+0.055	+0.796	<.001	.003	3	5
CNS	Positive regulation of protein modification by small protein conjugation or removal →	+0.054	+0.801	<.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.062	+0.105	.003	.005	2	6
UPPER_AERODIGESTIVE_TRACT	Regulation of protein K48-linked ubiquitination →	+0.140	+0.177	.002	.003	3	5
SOFT_TISSUE	Transferrin transport →	+0.110	+0.746	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,101 associations by consensus.

Stress granule assembly by RIMS1 expression — LUNG_SCLC

Explore this box plot interactively →