RHOA-IT1

Across TCGA patient cohorts, RHOA-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,548 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHOA-IT1-associated proteins across cancer lineages are LMNB2_T34, HSPH1, and MMRN1. Each is linked with RHOA-IT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RHOA-IT1-to-partner and partner-to-RHOA-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOA-IT1 versus LMNB2_T34 in PDAC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOA-IT1→partner) and Y-score (partner→RHOA-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LMNB2_T34 →	+0.653	+0.496	.001	<.001	3	4
BRCA	HSPH1 →	-0.373	-0.554	.003	.001	3	4
GBM	MMRN1 →	+0.628	+0.430	<.001	<.001	3	3
GBM	OGN →	+0.901	+0.295	.002	.004	2	4
LSCC	PDGFRB →	+0.359	+0.355	.002	.006	3	3
CCRCC	SHMT2 →	-0.441	-0.398	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,548 associations by consensus.

RHOA-IT1 vs LMNB2_T34 — PDAC

Explore this scatter interactively →