RGS8

Across TCGA patient cohorts, RGS8 protein abundance is significantly associated with the RNA expression of many other genes, with 547 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RGS8-associated genes across cancer lineages are CCDC6, GHR, and EHHADH. Each is linked with RGS8 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS8-to-partner and partner-to-RGS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS8 versus CCDC6 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS8→partner) and Y-score (partner→RGS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCDC6 →	+0.919	+0.310	.001	.009	2	1
GBM	GHR →	+1.170	+0.250	.009	.002	2	1
GBM	EHHADH →	+0.966	+0.310	.005	.009	2	1
GBM	GHRH →	+0.473	+0.279	.004	.007	2	1
GBM	TRMT1L →	+0.573	+0.309	.002	.009	2	1
GBM	LGR5 →	+1.840	+0.236	.004	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 547 associations by consensus.

RGS8 vs CCDC6 — GBM

Explore this scatter interactively →