RGS2

Across TCGA cell cohorts, RGS2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,316 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible RGS2-associated genes across cancer lineages are CCM2, ABTB2, and SLC15A3. Each is linked with RGS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RGS2-to-partner and partner-to-RGS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS2 versus CCM2 in KIDNEY, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS2→partner) and Y-score (partner→RGS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	CCM2 →	+0.658	+0.649	.001	<.001	3	4
BLOOD_Lymphoma	ABTB2 →	+2.420	+1.906	<.001	.003	3	4
SKIN	SLC15A3 →	+1.989	+1.330	.001	.006	3	3
SOFT_TISSUE	ITGB8 →	+2.110	+2.429	.002	.006	2	4
SOFT_TISSUE	BCL2A1 →	+5.950	+2.429	<.001	.006	3	3
OVARY	SGK2 →	+2.402	+1.106	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,316 associations by consensus.

RGS2 vs CCM2 — KIDNEY

Explore this scatter interactively →