RGS14

Across TCGA patient cohorts, RGS14 protein abundance is significantly associated with the RNA expression of many other genes, with 14,907 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS14-associated genes across cancer lineages are CYTH4, NCF4, and CSF2RB. Each is linked with RGS14 in more than 6 cancer types. Because this analysis shows association rather than direction, both RGS14-to-partner and partner-to-RGS14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS14 versus CYTH4 in HNSC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS14→partner) and Y-score (partner→RGS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTH4 →	+1.014	+0.318	<.001	<.001	3	7
LSCC	NCF4 →	+0.928	+0.535	<.001	<.001	3	7
LSCC	CSF2RB →	+1.125	+0.489	<.001	<.001	3	7
LSCC	IL18RAP →	+0.897	+0.402	<.001	<.001	3	7
LSCC	SASH3 →	+1.003	+0.426	<.001	<.001	3	7
HNSC	ARHGAP9 →	+0.928	+0.297	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,907 associations by consensus.

RGS14 vs CYTH4 — HNSC

Explore this scatter interactively →