RGS1

Across TCGA patient cohorts, RGS1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,764 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS1-associated genes across cancer lineages are ZNF831, PIK3R5, and SLAMF6. Each is linked with RGS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RGS1-to-partner and partner-to-RGS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS1 versus ZNF831 in PDAC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS1→partner) and Y-score (partner→RGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ZNF831 →	+0.964	+0.655	.005	<.001	3	4
LSCC	PIK3R5 →	+0.933	+0.634	<.001	<.001	3	4
PDAC	SLAMF6 →	+1.458	+0.715	.004	<.001	3	4
LSCC	KLHL6 →	+0.781	+0.438	<.001	<.001	3	4
PDAC	CELF2-AS1 →	+1.334	+0.707	.004	<.001	3	4
PDAC	LINC00426 →	+1.108	+0.734	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,764 associations by consensus.

RGS1 vs ZNF831 — PDAC

Explore this scatter interactively →