RFX3

Across TCGA patient cohorts, RFX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,304 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RFX3-associated proteins across cancer lineages are RFX3_S155, PSIP1, and PSIP1_S129. Each is linked with RFX3 in more than 7 cancer types. Because this analysis shows association rather than direction, both RFX3-to-partner and partner-to-RFX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX3 versus RFX3_S155 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX3→partner) and Y-score (partner→RFX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFX3_S155 →	+0.864	+0.814	<.001	<.001	3	8
GBM	PSIP1 →	+0.571	+0.921	<.001	<.001	3	6
HNSC	PSIP1_S129 →	+0.761	+0.786	<.001	<.001	3	6
UCEC	IFT140 →	+0.488	+0.656	<.001	.001	3	5
LSCC	PSIP1_S106 →	+0.488	+0.572	<.001	<.001	3	5
HNSC	CHAMP1 →	+0.341	+0.775	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,304 associations by consensus.

RFX3 vs RFX3_S155 — LSCC

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