RFX3

Across TCGA cell cohorts, RFX3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,008 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RFX3-associated genes across cancer lineages are RANBP6, ZDHHC21, and KDM4C. Each is linked with RFX3 in more than 15 cancer types. Because this analysis shows association rather than direction, both RFX3-to-partner and partner-to-RFX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX3 versus RANBP6 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.51.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX3→partner) and Y-score (partner→RFX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RANBP6 →	+1.491	+0.787	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	ZDHHC21 →	+1.682	+1.040	<.001	<.001	3	16
STOMACH	KDM4C →	+1.379	+1.008	<.001	<.001	3	15
OVARY	SNAPC3 →	+1.013	+0.760	<.001	<.001	3	15
URINARY_TRACT	PSIP1 →	+1.838	+0.839	.005	<.001	2	16
BREAST	KIAA2026 →	+0.986	+0.712	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,008 associations by consensus.

RFX3 vs RANBP6 — UPPER_AERODIGESTIVE_TRACT

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