Across TCGA cell cohorts, RFPL4A mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RFPL4A-associated genes across cancer lineages are OXT, AVPR1B, and KRTAP9-7. Each is linked with RFPL4A in more than 1 cancer types. Because this analysis shows association rather than direction, both RFPL4A-to-partner and partner-to-RFPL4A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL4A→partner) and Y-score (partner→RFPL4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OXT →	+0.063	+4.977	<.001	.007	3	1
SKIN	AVPR1B →	+0.006	+5.415	.007	.004	3	1
LUNG_SCLC	KRTAP9-7 →	+0.073	+5.643	<.001	.002	3	1
LUNG_SCLC	KRTAP9-6 →	+0.136	+5.643	<.001	.002	3	1
LUNG_NSCLC_LUAD	PTH →	+0.045	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	TEX26 →	+0.025	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

RFPL4A survival (RNA) · tumor vs normal (RNA) · all RFPL4A data types