RETN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RETN protein abundance is significantly associated with the RNA expression of many other genes, with 14,264 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RETN-associated genes across cancer lineages are CLEC4E, CEACAM3, and ADGRG3. Each is linked with RETN in more than 8 cancer types. Because this analysis shows association rather than direction, both RETN-to-partner and partner-to-RETN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RETN versus CLEC4E in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RETN→partner) and Y-score (partner→RETN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCLEC4E →+1.123+0.967<.001<.00139
LSCCCEACAM3 →+0.924+1.433<.001<.00139
PDACADGRG3 →+1.240+1.237<.001<.00139
LSCCFCGR3B →+1.829+1.275<.001<.00139
HNSCPROK2 →+1.287+1.124<.001<.00139
OVCCL20 →+2.300+1.130.001.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,264 associations by consensus.

RETN vs CLEC4E — UCEC

Per-sample scatter of RETN vs CLEC4E in UCEC (Pearson r = 0.51).

Explore this scatter interactively →

Exploration