REPS2

Across TCGA patient cohorts, REPS2 mutation is significantly associated with the RNA expression of many other genes, with 5,045 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REPS2-associated genes across cancer lineages are SNORD3H, RNU7-128P, and RNA5SP116. Each is linked with REPS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both REPS2-to-partner and partner-to-REPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD3H grouped by REPS2-low versus REPS2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REPS2→partner) and Y-score (partner→REPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORD3H →	+0.354	+5.288	<.001	.006	3	2
LUAD	RNU7-128P →	+0.731	+5.000	<.001	.002	3	2
LGG	RNA5SP116 →	+0.378	+7.977	<.001	.007	3	2
LUSC	C14orf177 →	+0.206	+4.261	.005	.008	3	2
LUSC	RN7SKP35 →	+0.362	+5.417	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.037	+2.437	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,045 associations by consensus.

SNORD3H by REPS2 expression — BRCA

Explore this box plot interactively →