REG4

Across TCGA patient cohorts, REG4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,760 significant associations in total. COAD shows the largest number of these associations.

The most reproducible REG4-associated genes across cancer lineages are IL1R2, PPARG, and CAPN5. Each is linked with REG4 in more than 2 cancer types. Because this analysis shows association rather than direction, both REG4-to-partner and partner-to-REG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REG4 versus IL1R2 in LUAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REG4→partner) and Y-score (partner→REG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL1R2 →	+1.948	+2.238	.001	.008	3	2
LUAD	PPARG →	+1.426	+2.517	.002	.007	3	2
LUAD	CAPN5 →	+2.329	+2.934	.001	.008	3	2
LUAD	TFF2 →	+7.634	+2.490	.009	.004	2	3
LUAD	ALDH1A1 →	+2.224	+2.107	.001	.009	3	2
LUAD	AMN →	+1.776	+1.661	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,760 associations by consensus.

REG4 vs IL1R2 — LUAD

Explore this scatter interactively →