REG1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, REG1B protein abundance is significantly associated with the protein abundance of many other proteins, with 3,943 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible REG1B-associated proteins across cancer lineages are THY1, REG1A, and LMOD1_S59. Each is linked with REG1B in more than 1 cancer types. Because this analysis shows association rather than direction, both REG1B-to-partner and partner-to-REG1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REG1B versus THY1 in PDAC, with a Pearson correlation of -0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (REG1B→partner) and Y-score (partner→REG1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACTHY1 →-0.554-1.341<.001<.00132
COADREG1A →+3.237+2.897<.001<.00132
PDACLMOD1_S59 →-1.347-2.150.003.00132
COADMAPRE1 →-0.413-1.890<.001<.00132
COADPSAT1 →+0.981+2.445<.001.00132
PDACARPC3 →-0.282-0.961<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,943 associations by consensus.

REG1B vs THY1 — PDAC

Per-sample scatter of REG1B vs THY1 in PDAC (Pearson r = -0.36).

Explore this scatter interactively →

Exploration