REG1B

Across TCGA cell cohorts, REG1B RNA expression is significantly associated with the mutation status of many other genes, with 375 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible REG1B-associated genes across cancer lineages are TAP2, SLC12A6, and LTF. Each is linked with REG1B in more than 2 cancer types. Because this analysis shows association rather than direction, both REG1B-to-partner and partner-to-REG1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAP2 grouped by REG1B-low versus REG1B-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REG1B→partner) and Y-score (partner→REG1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAP2 →	+4.734	+0.034	.002	<.001	3	3
BREAST	SLC12A6 →	+5.169	+1.039	.005	<.001	3	3
LUNG_NSCLC_LUAD	LTF →	+4.734	+0.029	.002	<.001	3	2
LUNG_NSCLC_LUAD	CBX2 →	+3.564	+0.024	.001	<.001	3	2
LARGE_INTESTINE	ZNF570 →	+3.196	+3.867	.007	<.001	3	2
LARGE_INTESTINE	OPHN1 →	+2.518	+2.209	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 375 associations by consensus.

TAP2 by REG1B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →