REEP2

Across TCGA patient cohorts, REEP2 mutation is significantly associated with the RNA expression of many other genes, with 128 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REEP2-associated genes across cancer lineages are SEPTIN14P24, PDE4B-AS1, and EIF3JP1. Each is linked with REEP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both REEP2-to-partner and partner-to-REEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN14P24 grouped by REEP2-low versus REEP2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP2→partner) and Y-score (partner→REEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SEPTIN14P24 →	+0.405	+5.343	<.001	.006	3	2
SKCM	PDE4B-AS1 →	+0.068	+3.180	.004	.004	3	2
UCEC	EIF3JP1 →	+0.217	+2.620	<.001	.004	3	2
UCEC	LINC01687 →	+0.360	+2.535	<.001	.004	3	2
UCEC	RPL30P12 →	+0.276	+2.649	<.001	.004	3	2
HNSC	MIR154 →	+0.388	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 128 associations by consensus.

SEPTIN14P24 by REEP2 expression — LUAD

Explore this box plot interactively →