REC114

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, REC114 mutation is significantly associated with the RNA expression of many other genes, with 283 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REC114-associated genes across cancer lineages are LINC01995, RNU1-34P, and RNU6ATAC25P. Each is linked with REC114 in more than 1 cancer types. Because this analysis shows association rather than direction, both REC114-to-partner and partner-to-REC114 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REC114→partner) and Y-score (partner→REC114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01995 →+0.369+3.992<.001.00632
LUSCRNU1-34P →+0.266+7.327.001<.00132
LUSCRNU6ATAC25P →+0.325+5.337<.001.00632
UCECRN7SL191P →+0.295+3.274<.001.00132
UCECYTHDF3-AS1 →+0.944+3.375<.001.00531
UCECCOPS8P1 →+0.117+2.900<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 283 associations by consensus.

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