RCC1

Across TCGA patient cohorts, RCC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,156 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RCC1-associated proteins across cancer lineages are MCM4, MCM6, and YTHDF2. Each is linked with RCC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both RCC1-to-partner and partner-to-RCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RCC1 versus MCM4 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC1→partner) and Y-score (partner→RCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM4 →	+0.738	+0.540	<.001	<.001	3	9
GBM	MCM6 →	+0.856	+0.592	<.001	<.001	3	9
GBM	YTHDF2 →	+0.385	+0.607	<.001	<.001	3	9
GBM	CDK1 →	+0.753	+0.647	<.001	<.001	3	9
GBM	MCM2 →	+0.737	+0.501	<.001	<.001	3	8
GBM	MCM2_S139 →	+0.717	+0.537	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,156 associations by consensus.

RCC1 vs MCM4 — GBM

Explore this scatter interactively →