RBSN

Across TCGA cell cohorts, RBSN mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RBSN-associated genes across cancer lineages are OR56A1, RGR, and CLRN1. Each is linked with RBSN in more than 1 cancer types. Because this analysis shows association rather than direction, both RBSN-to-partner and partner-to-RBSN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by RBSN-low versus RBSN-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBSN→partner) and Y-score (partner→RBSN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR56A1 →	+0.058	+4.276	<.001	.007	3	2
URINARY_TRACT	RGR →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	CLRN1 →	+0.033	+5.087	<.001	.004	3	1
URINARY_TRACT	SLC35G3 →	+0.006	+5.087	<.001	.004	3	1
SOFT_TISSUE	TGM7 →	+0.006	+5.369	<.001	.004	3	1
SOFT_TISSUE	KRTAP20-2 →	+0.122	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

OR56A1 by RBSN expression — BLOOD_Leukemia

Explore this box plot interactively →