RBM26

Across TCGA cell cohorts, RBM26 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RBM26-associated genes across cancer lineages are AADACL3, TRIM64B, and ASB17. Each is linked with RBM26 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM26-to-partner and partner-to-RBM26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AADACL3 grouped by RBM26-low versus RBM26-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM26→partner) and Y-score (partner→RBM26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	AADACL3 →	+0.006	+5.000	<.001	.006	3	1
PANCREAS	TRIM64B →	+0.006	+5.614	<.001	.002	3	1
OVARY	ASB17 →	+0.011	+3.807	<.001	.009	3	1
OVARY	KLHL40 →	+0.005	+3.865	.005	.001	3	1
OVARY	OR2AK2 →	+0.044	+3.444	.001	.003	3	1
OVARY	OR2H1 →	+0.018	+3.444	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

AADACL3 by RBM26 expression — PANCREAS

Explore this box plot interactively →