RBM26

Across TCGA pan-cancer cohorts, RBM26 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RBM26’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RBM26 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBM26 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, COAD, and BLCA are the cancer types where RBM26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBM26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.689	<.001	12	view →
COAD	Male	II,III,IV	+0.993	<.001	10	view →
BLCA	All	All	+0.476	<.001	8	view →
THCA	All	II,III,IV	−0.418	<.001	8	view →
KICH	Female	II,III,IV	−1.054	<.001	7	view →
STAD	Male	II,III,IV	+0.882	<.001	7	view →
LIHC	Female	II,III,IV	+0.806	<.001	7	view →
KIRC	All	All	+0.271	<.001	6	view →
CHOL	Male	All	+1.696	<.001	5	view →
KIRP	All	IV	+0.747	.028	2	view →
READ	All	All	+0.666	.013	2	view →
UCEC	All	All	−0.339	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RBM26–HNSC

Open the HNSC breakdown →