RBM23

Across TCGA patient cohorts, RBM23 mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RBM23-associated genes across cancer lineages are MIR874, TOMM22P5, and HM13. Each is linked with RBM23 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBM23-to-partner and partner-to-RBM23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR874 grouped by RBM23-low versus RBM23-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBM23→partner) and Y-score (partner→RBM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR874 →	+0.349	+3.681	<.001	.005	3	2
BLCA	TOMM22P5 →	+0.257	+4.009	<.001	.003	3	2
UCEC	HM13 →	-0.434	-3.676	.003	.001	3	2
UCEC	SPRYD7 →	+0.429	+3.593	.001	.001	3	2
UCEC	WHAMM →	+0.391	+3.032	.002	<.001	3	2
UCEC	RNU6-649P →	+0.183	+2.434	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

MIR874 by RBM23 expression — BLCA

Explore this box plot interactively →