Q-omics provides the consensus-scored MIR874 profile across patient tissues and cancer cell-line models. MIR874 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in DLBC. Among the 18 cancer types available for tumor–normal comparison, MIR874 is differentially expressed in 2, with the highest sampling consensus in KIRC. Additionally, MIR874 RNA expression shows 8,112 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight DLBC, KIRC, and GBM as cancer lineages where MIR874 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR874 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR874 survival associations across molecular data types. MIR874 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR874 RNA expression–survival associations across cancer types. High MIR874 expression shows unfavorable associations in DLBC, LUSC, READ, CESC and KIRP, but favorable associations in LUAD. The DLBC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify DLBC as the clearest survival context for MIR874 RNA expression.
This table summarizes MIR874 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR874. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR874 shows lower tumor expression in KIRC and THCA. The KIRC box plot shows higher MIR874 RNA expression in normal versus tumor tissue (log2 FC = −0.071, t-test p = .001).
This table shows molecular features associated with MIR874 in patient tissues and cancer cell lines. In patient samples, MIR874 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
