Across TCGA pan-cancer cohorts, MIR874 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR874’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR874 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR874 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC and THCA are the cancer types where MIR874 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR874 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.071	.001	4	view →
THCA	Male	All	−0.281	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MIR874 RNA expression & survival · all MIR874 data types