RBL1

Across TCGA cell cohorts, RBL1 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RBL1-associated genes across cancer lineages are ASB11, OR52L1, and VN1R2. Each is linked with RBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RBL1-to-partner and partner-to-RBL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB11 grouped by RBL1-low versus RBL1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBL1→partner) and Y-score (partner→RBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ASB11 →	+0.052	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	OR52L1 →	+0.053	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	VN1R2 →	+0.009	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	TEX51 →	+0.019	+4.643	<.001	.005	3	1
OVARY	GUCA1C →	+0.952	+3.700	<.001	.004	3	1
LARGE_INTESTINE	TNP1 →	+0.087	+3.415	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

ASB11 by RBL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →