RBAK-RBAKDN

Across TCGA patient cohorts, RBAK-RBAKDN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,470 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RBAK-RBAKDN-associated GO terms across cancer lineages are Interstrand cross-link repair, Microtubule nucleation, and Centriole-centriole cohesion. Each is linked with RBAK-RBAKDN in more than 14 cancer types. Because this analysis shows association rather than direction, both RBAK-RBAKDN-to-partner and partner-to-RBAK-RBAKDN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by RBAK-RBAKDN-low versus RBAK-RBAKDN-high in KICH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RBAK-RBAKDN→partner) and Y-score (partner→RBAK-RBAKDN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	Interstrand cross-link repair →	+0.025	+0.159	<.001	<.001	3	13
MESO	Microtubule nucleation →	+0.039	+0.127	<.001	<.001	3	13
KICH	Centriole-centriole cohesion →	+0.030	+0.176	.001	<.001	3	13
UVM	Microtubule polymerization or depolymerization →	+0.037	+0.105	<.001	<.001	3	13
KICH	Cytoplasmic microtubule organization →	+0.023	+0.188	<.001	<.001	3	13
KIRP	Establishment of mitotic sister chromatid cohesion →	+0.043	+0.108	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,470 associations by consensus.

Interstrand cross-link repair by RBAK-RBAKDN expression — KICH

Explore this box plot interactively →