RBAK-RBAKDN

Across TCGA pan-cancer cohorts, RBAK-RBAKDN RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RBAK-RBAKDN’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RBAK-RBAKDN RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RBAK-RBAKDN is over-expressed in tumor, although a few such as UCEC and PRAD show the opposite, repressed pattern.

KIRP, HNSC, and UCEC are the cancer types where RBAK-RBAKDN tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RBAK-RBAKDN RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.329	<.001	9	view →
HNSC	Male	IV	+0.280	<.001	8	view →
UCEC	All	All	−0.152	<.001	6	view →
KIRC	Male	All	+0.146	<.001	5	view →
LIHC	All	All	+0.119	.001	5	view →
KICH	Male	IV	+0.353	.007	3	view →
PAAD	All	All	+0.267	.028	2	view →
PRAD	All	All	−0.072	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RBAK-RBAKDN–KIRP

Open the KIRP breakdown →