RBAK-RBAKDN

Across TCGA pan-cancer cohorts, RBAK-RBAKDN RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RBAK-RBAKDN data layer compared with 2 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher RBAK-RBAKDN RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RBAK-RBAKDN expression acts as an unfavorable survival marker, although some lineages such as SKCM and LGG show a favorable association.

KICH, SKCM, and BLCA are the cancer types where RBAK-RBAKDN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	III,IV	0.260	1.000	<.001	56	view →
SKCM	OS	Tertile	II,III,IV	0.873	0.770	.002	39	view →
BLCA	DFS	Median	IV	0.263	0.431	.007	29	view →
KIRP	OS	Quartile	All	0.816	0.952	.004	24	view →
KIRC	DFS	Tertile	All	0.546	0.727	.003	22	view →
ACC	OS	Quartile	All	0.719	0.947	.010	22	view →
LGG	DFS	Quartile	All	0.929	0.775	.003	21	view →
CHOL	OS	Tertile	All	1.000	0.213	.013	18	view →
SCLC	OS	Quartile	All	0.857	0.667	.012	10	view →
LUAD	DFS	Quartile	IV	0.693	0.107	.024	9	view →
UCS	OS	Tertile	III,IV	0.175	0.583	.032	6	view →
OV	DFS	Quartile	IV	0.318	0.520	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RBAK-RBAKDN–KICH (DFS)

Open the KICH breakdown →