RB1-DT

Across TCGA patient cohorts, RB1-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 13,684 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RB1-DT-associated proteins across cancer lineages are HK3, MNDA, and MAN2A1. Each is linked with RB1-DT in more than 5 cancer types. Because this analysis shows association rather than direction, both RB1-DT-to-partner and partner-to-RB1-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RB1-DT versus HK3 in GBM, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RB1-DT→partner) and Y-score (partner→RB1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HK3 →	-1.031	-0.429	<.001	<.001	3	6
GBM	MNDA →	-0.728	-0.278	<.001	.003	3	6
LSCC	MAN2A1 →	-0.392	-0.316	<.001	<.001	3	5
BRCA	NCF1 →	-0.547	-0.324	<.001	<.001	3	5
GBM	NCF2 →	-0.662	-0.308	.001	.002	3	5
GBM	PARVG →	-0.359	-0.290	.005	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,684 associations by consensus.

RB1-DT vs HK3 — GBM

Explore this scatter interactively →