RASSF10-DT

Across TCGA pan-cancer cohorts, RASSF10-DT RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RASSF10-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RASSF10-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated RASSF10-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, LGG, and UCEC are the cancer types where RASSF10-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.858	0.749	<.001	73	view →
LGG	DFS	Median	All	0.653	0.818	<.001	54	view →
UCEC	DFS	Quartile	All	0.579	0.769	<.001	32	view →
LUSC	DFS	Median	III,IV	0.363	0.652	.005	30	view →
KIRP	DFS	Median	All	1.000	0.779	.001	30	view →
HNSC	DFS	Median	IV	0.433	0.244	.005	29	view →
LUAD	OS	Tertile	III,IV	0.567	0.191	.005	27	view →
UVM	DFS	Tertile	All	0.349	0.786	.005	18	view →
SKCM	OS	Quartile	All	0.813	0.891	.006	13	view →
ACC	OS	Tertile	All	0.291	0.663	.029	9	view →
LIHC	DFS	Tertile	III,IV	0.131	0.349	.012	9	view →
PCPG	DFS	Tertile	All	0.533	0.855	.034	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RASSF10-DT–KIRC (OS)

Open the KIRC breakdown →