RASSF10-DT

Across TCGA pan-cancer cohorts, RASSF10-DT RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of RASSF10-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RASSF10-DT RNA is repressed in tumor relative to normal tissue. In most cancer types RASSF10-DT is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where RASSF10-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RASSF10-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−1.089	<.001	12	view →
COAD	Male	All	+0.742	<.001	10	view →
KIRP	All	III,IV	−1.045	<.001	9	view →
THCA	Male	All	−0.257	<.001	7	view →
BLCA	All	All	+0.623	.006	6	view →
LUSC	All	All	+0.655	<.001	5	view →
KICH	Male	III,IV	−1.415	.005	4	view →
BRCA	Female	All	−0.846	<.001	4	view →
HNSC	All	All	+0.400	.010	4	view →
PRAD	All	All	−0.653	<.001	2	view →
LUAD	All	All	+0.342	.008	2	view →
STAD	All	IV	−1.250	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

RASSF10-DT–KIRC

Open the KIRC breakdown →