RASL11B

Across TCGA patient cohorts, RASL11B mutation is significantly associated with the RNA expression of many other genes, with 721 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL11B-associated genes across cancer lineages are HMGN1P34, RPL31P53, and RBMY2DP. Each is linked with RASL11B in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL11B-to-partner and partner-to-RASL11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGN1P34 grouped by RASL11B-low versus RASL11B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL11B→partner) and Y-score (partner→RASL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	HMGN1P34 →	+0.175	+4.433	<.001	.007	3	2
BLCA	RPL31P53 →	+0.078	+4.562	<.001	.006	3	2
BRCA	RBMY2DP →	+0.029	+9.057	<.001	.003	3	2
SKCM	RNU6-491P →	+0.323	+7.816	<.001	.008	3	2
BRCA	MIR6082 →	+0.281	+8.471	<.001	.005	3	1
BLCA	SLC29A4P2 →	+0.024	+5.033	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 721 associations by consensus.

HMGN1P34 by RASL11B expression — BLCA

Explore this box plot interactively →