RASL11A

Across TCGA patient cohorts, RASL11A mutation is significantly associated with the RNA expression of many other genes, with 1,107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL11A-associated genes across cancer lineages are MIR3118-3, RN7SKP286, and RNA5SP422. Each is linked with RASL11A in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL11A-to-partner and partner-to-RASL11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3118-3 grouped by RASL11A-low versus RASL11A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL11A→partner) and Y-score (partner→RASL11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR3118-3 →	+0.558	+8.471	<.001	.005	3	2
UCEC	RN7SKP286 →	+0.038	+3.738	<.001	.009	3	2
UCEC	RNA5SP422 →	+0.773	+2.140	<.001	.001	3	2
UCEC	RNA5SP416 →	+0.474	+2.124	<.001	.002	3	2
UCEC	RNA5SP415 →	+0.432	+2.073	<.001	.005	3	2
UCEC	RNA5SP412 →	+0.552	+1.867	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

MIR3118-3 by RASL11A expression — BRCA

Explore this box plot interactively →