RASL10A

Across TCGA patient cohorts, RASL10A mutation is significantly associated with the RNA expression of many other genes, with 90 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RASL10A-associated genes across cancer lineages are MIR513B, RNA5SP239, and RN7SL584P. Each is linked with RASL10A in more than 1 cancer types. Because this analysis shows association rather than direction, both RASL10A-to-partner and partner-to-RASL10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR513B grouped by RASL10A-low versus RASL10A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASL10A→partner) and Y-score (partner→RASL10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR513B →	+0.469	+3.621	<.001	.003	3	2
COAD	RNA5SP239 →	+0.623	+7.741	<.001	.009	3	1
COAD	RN7SL584P →	+1.423	+7.741	<.001	.009	3	1
COAD	RN7SKP260 →	+0.239	+7.741	<.001	.009	3	1
COAD	ZNF519P3 →	+0.039	+7.741	<.001	.009	3	1
COAD	RN7SL722P →	+0.134	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

MIR513B by RASL10A expression — UCEC

Explore this box plot interactively →