RASGRP4

Across TCGA patient cohorts, RASGRP4 protein abundance is significantly associated with the RNA expression of many other genes, with 11,138 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RASGRP4-associated genes across cancer lineages are SLC11A1, CD93, and CXCL3. Each is linked with RASGRP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both RASGRP4-to-partner and partner-to-RASGRP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RASGRP4 versus SLC11A1 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RASGRP4→partner) and Y-score (partner→RASGRP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC11A1 →	+1.666	+0.713	<.001	<.001	3	4
GBM	CD93 →	+1.277	+0.617	<.001	<.001	3	4
GBM	CXCL3 →	+1.460	+0.631	.008	.007	3	4
LSCC	CEACAM3 →	+0.842	+0.544	<.001	<.001	3	4
GBM	IFITM2 →	+1.130	+0.673	<.001	<.001	3	4
HNSC	KCNJ8 →	+1.159	+0.405	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,138 associations by consensus.

RASGRP4 vs SLC11A1 — GBM

Explore this scatter interactively →