RARG

Across TCGA patient cohorts, RARG mutation is significantly associated with the RNA expression of many other genes, with 2,167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RARG-associated genes across cancer lineages are MIR194-1, KIRREL3-AS3, and RNU6-163P. Each is linked with RARG in more than 2 cancer types. Because this analysis shows association rather than direction, both RARG-to-partner and partner-to-RARG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR194-1 grouped by RARG-low versus RARG-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RARG→partner) and Y-score (partner→RARG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR194-1 →	+0.647	+4.069	<.001	.005	3	3
HNSC	KIRREL3-AS3 →	+0.101	+3.051	<.001	.008	3	2
LIHC	RNU6-163P →	+0.317	+4.878	<.001	.005	3	2
BLCA	OR4F21 →	+0.015	+3.025	.006	.007	3	2
BLCA	RNU6-552P →	+0.151	+2.784	<.001	.004	3	2
UCEC	BBC3 →	+0.491	+1.925	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,167 associations by consensus.

MIR194-1 by RARG expression — CESC

Explore this box plot interactively →