Q-omics provides the consensus-scored KIRREL3-AS3 profile across patient tissues and cancer cell-line models. KIRREL3-AS3 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, KIRREL3-AS3 is differentially expressed in 3, with the highest sampling consensus in UCEC. Additionally, KIRREL3-AS3 RNA expression shows 9,623 significant gene co-expression associations, with the highest sampling consensus in PCPG. Together, these results highlight KIRC, UCEC, and PCPG as cancer lineages where KIRREL3-AS3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KIRREL3-AS3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KIRREL3-AS3 survival associations across molecular data types. KIRREL3-AS3 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KIRREL3-AS3 RNA expression–survival associations across cancer types. High KIRREL3-AS3 expression shows unfavorable associations in KIRC, DLBC, CHOL, ACC, BRCA and THCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify KIRC as the clearest survival context for KIRREL3-AS3 RNA expression.
This table summarizes KIRREL3-AS3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for KIRREL3-AS3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KIRREL3-AS3 shows lower tumor expression in KICH and higher tumor expression in UCEC and LUSC. The UCEC box plot shows higher KIRREL3-AS3 RNA expression in tumor versus normal tissue (log2 FC = +0.075, t-test p = .038).
This table shows molecular features associated with KIRREL3-AS3 in patient tissues and cancer cell lines. In patient samples, KIRREL3-AS3 shows the broadest associations at the RNA and protein expression levels, with PCPG recurring as the lineage with the largest associated feature set. In cancer cell lines, KIRREL3-AS3 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in STOMACH.
